Well your brother is facing a large fine. The No Insurance conviction will cost him a minimum $5000 fine. He should be prepared to show the court his financial situation and be able to prove that if the court imposes the $5000 fine it will cause undue hardship on him and/or his family. As far as the expired plates go he will face a much smaller fine, he should ask for the $50-$60 range.
As always, when facing charges of such a serious nature, one should consider speaking to a professional about the different options available.